The main incompatibility is that the base game Day 3 card has an option that may require you to put a Tyrant Encounter card on the top of your deck, and Rage of Tyranny doesn't use Tyrant Encounters.
The main incompatibility is that the base game Day 3 card has an option that may require you to put a Tyrant Encounter card on the top of your deck, and Rage of Tyranny doesn't use Tyrant Encounters.